tocilizumab - Actemra; RoActemra; interleukin-6 receptor monoclonal antibody, recombinant; IL-6r Mab -- Product Record

Interleukin-6 receptor Mab, rDNA

    Nomenclature:
      Interleukin-6 receptor Mab, rDNA [BIO]
      Actemra [TR]
      RoActemra [TR in Europe]
      tocilizumab [USAN INN]
      immunoglobulin G1, anti-(human interleukin 6 receptor) (human-mouse monoclonal MRA heavy chain), disulfide with human-mouse monoclonal MRA k-chain, dimmer  [CAS]
      375823-41-9 [CAS RN]
      BSF-2 [SY]
      MRA [SY]
      q [SY]
      recombinant humanised anti-human IL-6R monoclonal antibody [SY]
      RO4877533 [SY Roche]
      NDC 50242-135-01; NDC 50242-136-01; NDC 50242-137-01; NDC 50242-135-04; NDC 50242-136-04; NDC 50242-137-04 [NDC]

    molecular weight (kDa) = 149

    FDA Class:  Biologic BLA

    Year of approval (FDA) = 2010