Efungumab – Mycograb, monoclonal antibody, recombinant; HSP90 Mab -- Product Record

Heat shock protein Mab, rDNA

    Nomenclature:
      heat shock protein Mab, rDNA [BIO]
      efungumab [INN]
      immunoglobulin scFv fragment, anti-(heat shock protein 90 homolog from Candida albicans (yeast)), methionylalanyl-[human monoclonal HSP90mab VH domain (120 residues)]-tris[(tetraglycyl)seryl]-[human monoclonal HSP90mab V-KAPPA domain (107 residues)]-[arginyl-
      trialanyl-leucyl-glutamyl]-hexahistidine [CAS]
      heat shock protein 90 monoclonal antibody, recombinant [SY]
      HSP-90 Mab [SY]

    FDA Class:  Biologic BLA

Index Terms:

  • Product Class Index:
      antibodies (see also immune globulins; monoclonal antibodies)
      biopharmaceutical products
      exempt from CBER lot release requirements
      monoclonal antibodies, recombinant
  • Biological Index:
      Escherichia coli (E. coli)
      Harvard strain, Clostridium tetani
      hP67.6, monoclonal antibody
  • Chemical Index:
      histidine
      imidazole
      polygeline
  • Source/Host/Expression System: E. coli micbacecoli
  • Regulatory/Status Index:
      apheresis (hemapheresis)
      apheresis (hemapheresis)
      North American coral snake
      North American coral snake
      orphan status
      EU031 EU application denied
      UM999 Not Available/Not Marketed in US
      US01 FDA application withdrawn or rejected
      EM999 Not Available/Not Marketed in EU