Canakinumab - Ilaris; interleukin-1 beta monoclonal antibody; ACZ885 -- Product Record

Interleukin-1 Mab, rDNA

    Nomenclature:
      Interleukin-1 Mab, rDNA [BIO]
      Ilaris [TR]
      Canakinumab [USAN; FDA; INN]
      immunoglobulin G1, anti-(human interleukin 1β) (human clone ACZ885 heavy chain V region) [CAS]
      immunoglobulin G1, anti-(human interleukin-1 beta (IL-1β)) human monoclonal ACZ885; (1Glu>Glp)-γ1 heavy chain (221-214’)-disulfide with kappa light chain, dimer (227-227’’:230-230’’)-bisdisulfide [CAs]
      914613-48-2 [CAS RN]
      ACZ885 [SY]
      interleukin-1 beta monoclonal antibody [SY]
      Interleukin-1 Mab, rDNA [SY]
      NDC 0078-0582-61 [NDC]

    molecular weight (kDa) = 145.2

    FDA Class:  Biologic BLA

    Year of approval (FDA) = 2009