alipogene tiparvovec - Glybera; AMT-011; AAV1-LPL(S447X), recombinant; adenoassociated virus vector for delivery of human lipoprotein lipase (LPL) Ser(447)X -- Product Record

LPL gene therapy

    Nomenclature:
      Glybera [TR]
      alipogene tiparvovec [INN]
      recombinant adeno-associated virus serotype 1 (AAV1) vector expressing the S447X variant of the human lipoprotein lipase (LPL) gene [CAS]
      AAV1-LPL(S447X) [SY]
      AMT-011 [SY]
      human lipoprotein lipase (LPL) [SY]
      LPLSer(447)X gene therapy [SY]

    FDA Class:  Biologic BLA

Index Terms:

  • Product Class Index:
      biopharmaceutical products
      Gene Activation
      recombinant DNA
  • Biological Index:
      adenine triphosphate (ATP)
      cells, human
  • Chemical Index:
  • Source/Host/Expression System: adenovirus vector genetheradeno
  • Regulatory/Status Index:
      octoxynol (Triton X-100)
      EU200 Currently Approved in EU
      UM999 Not Available/Not Marketed in US
      US000 never filed/no plans
      EM001 Marketed Product in EU