elosulfase alfa - Vimizim; N-acetylgalactosamine-6-sulfatase; rhGALNS; BMN-110, elosulfase alfa; chondroitin sulfatase -- Product Record

N-acetylgalactosamine-6-sulfatase, rDNA

    Nomenclature:
      Vimizim [TR]
      elosulfase alfa [INN]
      N-acetylgalactosamine-6-sulfatase [SY]
      Human N-acetylgalactosamine-6-sulfatase (chondroitinsulfatase, galactose-6-sulfate sulfatase, EC=3.1.6.4) dimer (139-139')-disulfide glycosylated (produced by CHO cells) [CAS]
      9025-60-9 [CAS RN]
      BMN-110 [SY]
      chondroitin sulfatase [SY]
      rhGALNS [SY]

    molecular weight (kDa) = 110.8

    FDA Class:  Biologics BLA

Index Terms:

  • Product Class Index:
      biopharmaceutical products
      hamster source materials
      recombinant DNA
  • Biological Index:
      Chinese hamster ovary (CHO) cells
      chlortetracycline
  • Chemical Index:
  • Source/Host/Expression System: CHO mamrodhamcho
  • Regulatory/Status Index:
      approval dates uncertain (FDA reports erroneous, conflicting, or simply has lost the original approval dates) (FDAapproved)
      orphan status
      priority review status
      radioimmune conjugates<!-- radioconjugates -->
      EU002 EU application pending
      UM001 Marketed Product in US
      US200 Currently Approved in US
      EM999 Not Available/Not Marketed in EU