Abciximab - ReoPro; Platelet monoclonal antibody, recombinant chimeric -- Product Record

Platelet Mab Fab, rDNA

      Platelet Mab Fab, rDNA [BIO]
      ReoPro [TR (assigned to Eli Lilly & Co.)]
      CenteoRx [TR former in U.S.]
      Abciximab [FDA USAN INN BAN ]
      Immunoglobulin G, (human-mouse monoclonal c7E3 clone p7E3VGHhhCgamma4) Fab fragment anti-human glycoprotein IIb/IIIa receptor), disulfide with human-mouse monoclonal c7E3 clone p7E3VkappahCkappa light chain [Note, the large H and gamma4 in “p7E3VGHhhCgamma4” and the kappa in “E3VkappahCkappa” are subscripted and gamma and kappa are Greek symbols]. [CAS]
      143653-53-6 [CAS RN]
      7E3, human-murine monoclonal antibody [SY]
      anti-GPIIb/IIIa monoclonal antibody [SY]
      c7E3 [SY]
      c7E3 Fab fragment [SY]
      Fab fragment of the chimeric human-murine monoclonal antibody 7E3 [SY]
      GPIIb/IIIa monoclonal antibody [SY]
      human-murine monoclonal antibody 7E3 [SY]

    molecular weight (kDa) = 48

    FDA Class:  Biologic BLA

    Year of approval (FDA) = 1994