Reteplase - Retavase; Rapilysin; tissue plasminogen activator (tPA) mutein, recombinant -- Product Record

tPA, rDNA/PDL

    Nomenclature:
      tPA, rDNA/PDL [BIO]
      Retavase [TR]
      Reteplase [FDA INN]
      173-527-plasminogen activator (human tissue-type protein moiety reduced), 173-L-serine-174-L-tyrosine-175-L-glutamine- [CAS]
      133652-38-7 [CAS RN]
      BM-06022 [SY]
      fibrinokinase [SY]
      t-PA [SY]
      Tissue plasminogen activator, recombinant [SY]
      Rapilysin [TR former used by Roche in Europe]
      Ecokinase [TR former used by Galenus Mannheim, Germany
      ]
      NDC 57894-040-01; NDC 57894-040-02 [NUM NDC]
      C1736H2653N499O522S22 [MF USAN]
      39.57189 kDa [MW USAN]

    molecular weight (kDa) = 39.6

    FDA Class:  Biologic BLA

    Year of approval (FDA) = 1996