Status: withdrawn from the market

Organizations involved:

Wyeth – Manuf.; R&D; Tech.; Former

Cross ref: See the entries for a component vaccine, Tetanus Toxoid Adsorbed (#554). See the Tetanus Toxoid Vaccines (#543) and Diphtheria Toxoid Products (#418) entries. See also the DTP and DTaP vaccines from Wyeth incorporating this vaccine.

Description: Diphtheria & Tetanus Toxoids Adsorbed is a combination vaccine formulated by mixture of two vaccines, Tetanus Toxoid Adsorbed and Diphtheria Toxoid Adsorbed, from Wyeth (formerly Lederle Labs.). This combination was apparently used by Wyeth/Lederle for further manufacture of its DTP and DTaP vaccines.

Nomenclature: Diphtheria & Tetanus Toxoids Adsorbed/Wyeth [BIO]; Diphtheria & Tetanus Toxoids Adsorbed [FDA]

Companies.: The vaccine was manufactured by Wyeth Pharmaceuticals, FDA CBER est. no. 0003.

FDA class: Biologic PLA

CBER class: Multiple Antigen Preparations

Approvals: Date = unknown; original approval date no longer reported (lost) by FDA

Date = 19700911; first approval, according to the CBER/FDA database and other FDA sources (wrong). The proper names for this and other adsorbed toxoid-containing vaccines from Wyeth were changed on this date, with the product license revoked and granted (reissued) using the current proper name.

Indications: product insert/labeling not available

Status: Approval was voluntarily revoked by Wyeth in late 2003 (or early 2004). This vaccine was apparently used for further manufacture of DTP and DTaP vaccines by Wyeth. In Jan. 2001, Wyeth announced it was discontinuing manufacture of tetanus toxoid and vaccines containing a tetanus toxoid component, including this vaccine.