Oblimersen sodium - Genasense; augmerosen; G3139 -- Product Record

Bcl-2 Antisense Drug

    Nomenclature:
      Bcl-2 Antisense Drug [BIO]
      oblimersen sodium [FDA USAN]
      Genasense [TR]
      190977-41-4 [CAS RN]
      p-thiothymidylyl-(3'to 5')-2'-deoxy-P-thiocytidylyl-(3'to 5')-P-thiothymidylyl-(3'-->5')-2'-deoxy-P-thiocytidylyl-(3-->5')-2'-deoxy-P-thiocytidylyl-(3-->5')-2'-deoxy-P-thiocytidylyl-(3-->5')-2'-deoxy-P-thioadenylyl-(3-->5')-2'-deoxy-P-thioguanylyl-(3-->5')-2'-deoxy-P-thiocytidylyl-(3-->5')-2'-deoxy-P-thioguanylyl-(3-->5')-P-thiothymidylyl-(3-->5')-2'-deoxy-P-thioguanylyl-(3-->5')-2'-deoxy-P-thiocytidylyl-(3-->5')-2'-deoxy-P-thioguanylyl-(3-->5')-2'-deoxy-P-thiocytidylyl-(3-->5')-2'-deoxy-P-thiocytidylyl-(3-->5')-2'-deoxy-P-thioadenylyl-(3-->5')-thymidine heptadecasodium salt [CAS]
      augmerosen [SY]
      DNA, d(P-thio)(T-C-T-C-C-C-A-G-C-G-T-G-C-G-C-C-A-T) [SY]
      G 3139 [SY]
      G3139 [SY]

    FDA Class:  NDA Drug

Index Terms:

  • Product Class Index:
      antihemophilic factors
      non-Hodgkin's lymphoma (NHL)
      octoxynol (Triton X-100)
      phosphoric acid, meta-
      suspension cell culture
  • Biological Index:
      barium citrate
  • Chemical Index:
      Cottonmouth venom
  • Source/Host/Expression System: Synthetic
  • Regulatory/Status Index:
      accelerated approval (based on surrogate endpoints) (FDAapproved)
      apheresis (hemapheresis)
      approval dates uncertain (FDA reports erroneous, conflicting, or simply has lost the original approval dates) (FDAapproved)
      Cohn Fraction IV
      FDA application withdrawn
      North American coral snake
      North American coral snake
      orphan status
      priority review status
      EU002 EU application pending
      UM999 Not Available/Not Marketed in US
      US002 FDA application pending
      EM999 Not Available/Not Marketed in EU